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A2M in Tucson

What is A2M?

Alpha-2-Macroglobulin (A2M) therapy represents a significant advancement in the treatment of joint degeneration and arthritis. A2M is a naturally occurring protein in the blood that acts as a broad-spectrum protease inhibitor, targeting and neutralizing enzymes that degrade cartilage and contribute to osteoarthritis. The therapy involves concentrating this protein from a patient’s blood and injecting it directly into the affected joint or tissue, where it can prevent further cartilage breakdown and inflammation​.

What are the Benefits of A2M?

The benefits of A2M therapy are multifaceted. Firstly, it provides a potent defense against the enzymes responsible for cartilage degradation, which is crucial in slowing the progression of osteoarthritis. By inhibiting these harmful enzymes, A2M helps to preserve existing cartilage and joint function. Additionally, A2M has anti-inflammatory properties, reducing pain and swelling in the joint, which can significantly improve the quality of life for patients suffering from chronic joint pain. Some studies have also suggested that A2M injections may aid in the healing process of damaged tissues, further enhancing joint health and functionality​.


What does A2M procedure look like?

The process of administering A2M therapy is straightforward yet highly specialized. It begins with a blood drawn from the patient. The blood collected from the patient is then spun down in a centrifuge (similar to PRP) and filtered repeatedly to concentrate the A2M protein. This concentrated solution is injected into the affected area using ultrasound guidance to ensure precise delivery. Patients typically experience an initial period of soreness due to the injection, followed by significant improvements in pain and joint function within a few days as the A2M begins to take effect​.